Selected Publications:

Filatov, G.N., Aylwin, M.L., and White, M.M. (1993) Selective enhancement of the interaction of curare with the nicotinic acetylcholine receptor.
Mol. Pharmacol. 44:237-241. PDF File

O'Leary, M.E., Filatov, G.N., and White, M.M. (1994) Characterization of the
d-tubocurarine binding site of the Torpedo acetylcholine receptor. Am. J. Physiol. 266:C648-C653.

Aylwin, M.L., and White, M.M. (1994) Ligand-receptor interactions in the nicotinic acetylcholine receptor probed using multiple substitutions at conserved tyrosines in the
α subunit. FEBS Letts. 349: 99-103.

Aylwin, M.L., and White, M.M. (1994) Gating properties of mutant acetylcholine receptors.
Mol. Pharmacol. 46:1149-1155. PDF FIle

Filatov, G.N, and White, M.M. (1995) The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating.
Mol. Pharmacol. 48:379-384. PDF File

Yan, D., Pedersen, S.E., and White, M.M. (1998) Interaction of
d-tubocurarine analogs with the 5HT3 receptor. Neuropharmacology 37:251-257. PDF File

Yan, D., Schulte, M.K., Bloom, K.E., and White, M.M.(1999) Structural features of the ligand-binding domain of the serotonin 5HT
3 receptors. J. Biol. Chem. 274:5537-5541. PDF File

Kosolapov, A., Filatov, G.N., and White, M.M. (2000) Acetylcholine receptor gating is influenced by the polarity of amino acids at position 9’ in the M2 domain.
J. Membr. Biol. 174:191-197 PDF File

Yan, D. and White, M.M. (2002) Interaction of
d-tubocurarine analogs with mutant 5-HT3 receptors. Neuropharmacology 43: 367-373 PDF File

Yan, D. and White, M.M. (2005) Spatial orientation of the antagonist granisetron in the ligand-binding site of the 5-HT
3 receptor. Mol. Pharmacol. 68:365-371. PDF File

White, M.M. (2006) Pretty subunits all in a row:Using concatenated subunit constructs to force the expression of receptors with defined subunit stoichiometry and spatial arrangement.
Mol. Pharmacol. 68:365-371. PDF File

Yan, D., Meyer, J., and White, M.M. (2006) Mapping residues in the ligand-binding domain of the 5-HT
3 receptor onto d-tubocurarine structure. Mol. Pharmacol. 70:571-578. PDF FIle

Zhang, R., Wen, X., Militante, J., Hester, B., Rhubottom, H.E., Sun, H., Leidenheimer, N.J., Yan, D., White, M.M., and Machu, T.K. (2007) The role of Loop F residues in determining differential d-tubocurarine potencies in mouse and human 5-hydroxytryptamine
3A receptors. Biochemistry 46:1194-1204. PDF File

Borroni, V., Baier, C.J., Lang, T., Bonini, I., White, M.M., Garbus, I., and Barrantes, F.J. (2007) Cholesterol depletion activates rapid internalization of submicron-sized acetylcholine receptor domains at the cell membrane.
Mol. Membr. Biol. 24:1-15 PDF File

Nyce, H.L., Stober, S.T., Abrams, C.F., and White, M.M. (2010) Mapping spatial relationships between residues in the ligand-binding domain of the 5-HT3 receptor using “molecular rulers.”
Biophys. J. 98:1847-1855 PDF FIle