Selected
Publications:
Filatov, G.N., Aylwin, M.L., and White, M.M. (1993)
Selective enhancement of the interaction of curare with the
nicotinic acetylcholine receptor. Mol. Pharmacol.
44:237-241. PDF File
O'Leary, M.E., Filatov, G.N., and White, M.M. (1994)
Characterization of the d-tubocurarine binding site of the
Torpedo
acetylcholine
receptor. Am. J.
Physiol. 266:C648-C653.
Aylwin, M.L., and White, M.M. (1994) Ligand-receptor
interactions in the nicotinic acetylcholine receptor probed
using multiple substitutions at conserved tyrosines in
the α
subunit. FEBS Letts. 349: 99-103.
Aylwin, M.L., and White, M.M. (1994) Gating properties of
mutant acetylcholine receptors. Mol. Pharmacol.
46:1149-1155. PDF FIle
Filatov, G.N, and White, M.M. (1995) The role of conserved
leucines in the M2 domain of the acetylcholine receptor in
channel gating. Mol. Pharmacol.
48:379-384. PDF File
Yan, D., Pedersen, S.E., and White, M.M. (1998) Interaction
of d-tubocurarine analogs with the
5HT3 receptor. Neuropharmacology
37:251-257. PDF File
Yan, D., Schulte, M.K., Bloom, K.E., and White, M.M.(1999)
Structural features of the ligand-binding domain of the
serotonin 5HT3 receptors. J. Biol. Chem. 274:5537-5541. PDF File
Kosolapov, A., Filatov, G.N., and White, M.M. (2000)
Acetylcholine receptor gating is influenced by the polarity
of amino acids at position 9’ in the M2
domain. J. Membr.
Biol. 174:191-197 PDF File
Yan, D. and White, M.M. (2002) Interaction of
d-tubocurarine analogs with mutant
5-HT3 receptors. Neuropharmacology
43: 367-373 PDF File
Yan, D. and White, M.M. (2005) Spatial orientation of the
antagonist granisetron in the ligand-binding site of the
5-HT3 receptor. Mol. Pharmacol.
68:365-371. PDF File
White, M.M. (2006) Pretty subunits all in a row:Using
concatenated subunit constructs to force the expression of
receptors with defined subunit stoichiometry and spatial
arrangement. Mol.
Pharmacol. 68:365-371. PDF File
Yan, D., Meyer, J., and White, M.M. (2006) Mapping residues
in the ligand-binding domain of the 5-HT3
receptor onto
d-tubocurarine structure.
Mol.
Pharmacol. 70:571-578. PDF FIle
Zhang, R., Wen, X., Militante, J., Hester, B., Rhubottom,
H.E., Sun, H., Leidenheimer, N.J., Yan, D., White, M.M.,
and Machu, T.K. (2007) The role of Loop F residues in
determining differential d-tubocurarine potencies in mouse
and human 5-hydroxytryptamine3A
receptors.
Biochemistry
46:1194-1204. PDF File